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This report is the WHO's official record of data produced by its technical programmes and regional offices in close consultation with countries and in collaboration with researchers and development agencies. The WHO produces the statistics to provide an evidence base for strategies to improve global public health.

The report clearly shows that the global burden of disease is shifting from infectious diseases to non-communicable diseases, with chronic conditions such as heart disease and stroke now being the chief causes of death globally. The shifting trends indicate that leading infectious diseases — diarrhoea, HIV, tuberculosis, neonatal infections and malaria — will become less important causes of death globally over the next 20 years.

The report documents in detail "the levels of mortality in children and adults, patterns of morbidity and burden of disease, prevalence of risk factors such as smoking and alcohol consumption, use of health care, availability of health care workers, and health care financing."

This joint publication between the World Health Organization and the Global Forum for Health Research reveals mental health research capacity in 114 low-income and middle-income countries in Africa, Asia, and Latin America and the Caribbean. The extensive review identified over 10,000 articles, 4,633 mental health researchers and 3,829 other stakeholders. The authors argue that this is "the first systematic attempt to confirm the pressing needs of improving research capacity in mental health".

The publication provides useful details in table and charts, analysed by group of stakeholders and by region, on topics such as: researchers' profiles; priority-setting process; amount and type of research production; services and technical support available to them; courses and trainings offered; funding patterns; and dissemination of research findings. The appendix provides two extensive lists — by country — of policy and practice that resulted from research evidence, as well as research evidence that was never translated into policy and practice.

Nine recommendations indicate how the management of mental health research can be strengthened so that it meets the national needs of the countries as well as contributes to the global fund of knowledge. The authors say their report thus enables evidence-based decision-making in funding and priority setting in the area of mental health research in low-income and middle-income countries.

These consist of two reports: SuRF1(Surveillance of risk factors related to non-communicable diseases: current status of global data) and SuRF2 (Surveillance of chronic disease risk factors: country-level data and comparable estimates).

These reports are the result of a large WHO project to set up for the first time a global database of the prevalence of risk factors for non-communicable diseases collected from WHO member states. The first report is largely a collection of the country profiles; the second analyses the data to produce comparable estimates for risk factor prevalence in the countries. The WHO designed this as an advocacy tool to highlight where primary prevention and health promotion need to be directed.

The eight risk factors were chosen because they are easily measurable and theoretically can be changed through prevention efforts. They are: tobacco and alcohol use, patterns of physical inactivity, low fruit/vegetable intake, obesity (as measured by BMI), blood pressure, cholesterol and diabetes (measured by blood glucose).

The second report presents country-level estimates for overweight/obesity and systolic blood pressure. It also shows the attributable mortality and disease burden from all causes of death due to these overweight and high blood pressure for the 11 most populated countries. 

(See WHO Global InfoBase Online for electronically searchable data contained in the reports http://www.who.int/infobase/surf2/online.html.)

Chronic diseases — heart and lung disease, cancer and diabetes — are having a negative economic impact on both the developed and developing world, says this report, which is why they should be properly addressed by domestic and international policy makers. Compared to the epidemiological evidence on the rise of non-communicable diseases in developing nations, there is little information on how this increase will affect their economies.

This report investigates the demographics of the problem and finds that contrary to popular belief, the disproportionate burden of disease on the elderly does have economic implications. The reason is that though the elderly may not be part of the workforce, they are still consumers and therefore a part of the economic equation.

Whether approaches to tackling chronic diseases are cost-effective or not is a vital issue for countries whose health budgets are already overstretched — the report outlines some of the interventions that offer most bang for buck. The authors point out that strategies that work well in developed countries are not so effective in developing countries, and call for more research to assess what will be appropriate.

This extensive report was one of the first to document the scale of the problem of chronic diseases in developing countries, and crucially, to offer guidance on feasible and practical methods of tackling them.

The document starts by laying out in detail the profiles of chronic diseases in different countries, projections for the future, and how chronic diseases are linked with poverty. It also examines in depth the economic costs of such diseases and the macroeconomic consequences of not tackling them quickly enough. The authors outline interventions — whether community, workplace, or school — that have robust evidence supporting them.

The report ends with a call for a unifying framework of global health experts and stakeholders, in which the government has a key role. It also specifies what policymakers need to do to ensure that measures to tackle chronic diseases are put into action.

The report summarises the results of a survey of African Universities’ experiences in collaborating with scientists and institutions in developed countries. The study was carried out by the Association of Commonwealth Universities to provide background information to support the recent development thrust aimed at strengthening African universities through greater investment and North–South (and South–South) collaboration. It focuses primarily on social sciences and humanities research. The report presents empirical data on institutional goals, resource availability, prevalence and satisfaction with collaborative arrangements, challenges faced by individual researchers, capacity building as well as training and research support.

This paper presents a review of the challenges of international scholarly scientific collaboration. It looks at institutional constraints and points out that the challenges and problems multiply when collaborators come from different countries with differing conditions, resource endowments and institutional structures. It is easier to call for more and better forms of international collaboration than it is to design them. The report asserts that good design is helped by a better understanding of what collaboration is and how it has been carried out. It draws on social research insights to help reduce the transactional, financial, ethical and emotional costs of international linkages and exchange and provides a conceptual framework for thinking about international collaboration issues.

This chapter of the IPCC special report on climate change's regional impacts is one of the most authoritative sources on the issue, despite a considerable amount of work having been published since.

The chapter covers the regional climate, key vulnerabilities for various sectors, such as terrestrial ecosystems, water resources, agriculture and fisheries, coastal zones, human settlements and health. A synthesis outlines the potential impacts on the continent and lays out the key challenges that should guide further research.

This chapter should be read together with chapter 10 of the IPCC's 'Climate Change 2001' report. They cover similar ground, but various developments in research distinguish the two. The document is also available in French (PDF).

This chapter of the Third Assessment Report of the Intergovernmental Panel on Climate Change is the authoritative source on climate change impacts and vulnerabilities in Africa. It summarises much of the peer-reviewed literature that explains how Africa will fare in a changing climate.

Background information on why Africa is particularly vulnerable to the impacts of climate change is provided. The major issues of regional concern including unreliable water resources, food security, natural resource management and loss of biodiversity, human health, the built environment and infrastructure and desertification and how these will be compounded by projected climate change are discussed.

The chapter highlights the uncertainty of predicting climate change impacts in Africa and emphasises the existing diversity of African climates.

The provided synthesis of years of peer-reviewed research is essential reading for anyone interested in climate change in Africa. The text is also available as an html document.

This paper provides a call for a new Green Revolution focused on Africa. It summarises the successes and failures of the original Green Revolution, setting out the challenge of igniting a new one that can succeed in Africa.

The authors identify the need for more robust seed varieties, more trained scientists, improved inputs and cultivation practices, better supply and marketing infrastructure, and greater access to irrigation. Achieving these, say the authors, will require strong partnerships between philanthropists, governments, donors, research institutes and the private sector, as well as decisive leadership.

This draft report of the High-Level African Panel on Modern Biotechnology recommends that African governments prioritise biotechnology as a tool to promote development and integration. The panel advises African leaders on developments in biotechnology, capacity building needs, and measures for regional cooperation and regulatory harmonisation.

The report suggests measures to develop capacity, regulate biotechnology and improve North–South and South–South collaboration. It recommends a structure based on 'local innovation areas' where clusters of innovative companies, their suppliers and service providers, universities and research institutes are all concentrated in a small area.

This draft report is subject to ongoing consultation and is likely to undergo further development. It is an essential read for anyone tracking the evolution of high-level biotechnology policies in Africa.

This paper maps African countries' knowledge base through patent applications and publications. It shows South Africa as academically, and technically, the strongest country of the continent. The number of publications is growing in other African countries, but patenting remains limited all-round.

The paper ends on a positive note, arguing that African countries already possess the basis for knowledge-driven development.

This 200-page report provides background data and analysis on climate impacts in sub-Saharan Africa, and identifies 'hotspots' of environmental change. It maps current farming systems throughout the continent, as well as key indicators of climate change including number and length of growing seasons and annual rainfall. A map of 'vulnerability' across the continent is presented, based on natural, physical, social and human indicators, and financial capital under different climate scenarios.

Some of the uncertainties in the analysis are identified and the decision-making implications discussed. Although the maps do not disclose the causes of climate change in Africa, they do give policymakers warning of the communities and farming systems likely to suffer most.

The report points out that Africa will face some of the largest impacts despite its countries being among the world's lowest greenhouse gas emitters. Developed countries therefore have an ethical obligation to help the continent prepare for climate change impacts, say the authors, although they also emphasise the need for local communities to start implementing adaptation strategies for themselves.

This draft document contains general guidelines on the creation and governance of health research ethics committees (HRECs) in Nigeria.

It also lists the principal characteristics research projects need to demonstrate in order to gain HREC approval. Research in Nigeria must have social or scientific value, be scientifically valid, ensure fair selection of participants, minimise health risks and undergo independent review. In addition, all participants of research projects must give their informed consent and be respected at all times. All projects must adhere to good clinical and laboratory practices. Researchers must do all they can to ensure their work has a lasting impact — transferring technology where appropriate and contributing to capacity building efforts.

This article summarises the findings of a study undertaken by US-based academics at the Economic Research Service of the US Department of Agriculture and the State University of New Jersey.  The authors analysed data on the impact of the adoption of genetically modified Bacillus thuringiensis (Bt) maize on corn production in seven southern African countries:  Angola, Lesotho, Malawi, Mozambique, Swaziland, Zambia and Zimbabwe.  The report discusses the importance of corn in southern African farming and diets and describes the process of adoption of Bt corn, which was slow at first.

The study found that both large and small-scale farmers who planted Bt cotton benefited in terms of increased yields and reduced pesticide applications, although it was impossible to quantify the latter advantage in relation to smallholders.  Small farmers said that they liked the quality of the Bt corn varieties.

The report goes on to estimate the potential impact of improved corn yield on food security in the region.  The authors conclude by discussing possible measures that might encourage small farmers to adopt the new varieties.